{"id":15060,"date":"2018-01-30T16:33:26","date_gmt":"2018-01-30T15:33:26","guid":{"rendered":"https:\/\/medifactia.com\/pl\/validated-method\/"},"modified":"2023-12-21T13:33:21","modified_gmt":"2023-12-21T12:33:21","slug":"validated-method","status":"publish","type":"page","link":"https:\/\/medifactia.com\/pl\/validated-method\/","title":{"rendered":"Validated Method"},"content":{"rendered":"<div  class='flex_column av-aum4i1-8aabd5d562db71527b5508abddbe318f av_one_full  avia-builder-el-0  el_before_av_one_half  avia-builder-el-first  first flex_column_div  '     ><p>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-29qnkp-6938b89caf5c21e3ade9468d46cbb234\">\n#top .av-special-heading.av-29qnkp-6938b89caf5c21e3ade9468d46cbb234{\npadding-bottom:10px;\n}\nbody .av-special-heading.av-29qnkp-6938b89caf5c21e3ade9468d46cbb234 .av-special-heading-tag .heading-char{\nfont-size:25px;\n}\n.av-special-heading.av-29qnkp-6938b89caf5c21e3ade9468d46cbb234 .av-subheading{\nfont-size:15px;\n}\n<\/style>\n<div  class='av-special-heading av-29qnkp-6938b89caf5c21e3ade9468d46cbb234 av-special-heading-h1 blockquote modern-quote  avia-builder-el-1  el_before_av_textblock  avia-builder-el-first '><h1 class='av-special-heading-tag '  itemprop=\"headline\"  >Validated and Widely Accepted: A Clinical Solution<\/h1><div class=\"special-heading-border\"><div class=\"special-heading-inner-border\"><\/div><\/div><\/div><br \/>\n<section  class='av_textblock_section av-k2n7aoxx-c55814f175db2dc9f4fb36b93f89beed '   itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock'  itemprop=\"text\" ><p>The Transit-Pellets method, formerly known as the Abrahamsson method, is clinically useful in patients experiencing symptoms of a transit disturbance, which may have pathophysiological and clinical significance, such as chronic constipation or chronic diarrhoea. The Transit-Pellets principle involves the ingestion of ten Transit-Pellets radiopaque markers per day for six consecutive days, followed by a single abdominal X-ray or fluoroscopy on the seventh day to count the number of remaining markers. Colonic transit time is calculated as the mean oro-anal transit time (OATT, mouth-to-anus) for the daily marker doses swallowed. Because the colonic transit constitutes the main part of the mouth-to-anus transit time, OATT is used as a measure of colonic transit.<\/p>\n<p>The Transit-Pellets method is the leading technology used for colonic transit studies in regions such as Scandinavia, Europe, Australia, and New Zealand, and it has recently been introduced in the United States. With its proven track record of accuracy and reliability, the Transit-Pellets method and the Transit-Pellets device is the preferred choice of many medical professionals for colonic transit studies.<\/p>\n<\/div><\/section><\/p><\/div>\n<div class='flex_column_table av-6jak7d-586a08d8541bac0e2aace4a9f87edd49 sc-av_one_half av-equal-height-column-flextable'>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-6jak7d-586a08d8541bac0e2aace4a9f87edd49\">\n.flex_column.av-6jak7d-586a08d8541bac0e2aace4a9f87edd49{\npadding:30px 30px 30px 30px;\nheight:300px;\nbackground-color:#284868;\n}\n<\/style>\n<div  class='flex_column av-6jak7d-586a08d8541bac0e2aace4a9f87edd49 av_one_half  avia-builder-el-3  el_after_av_one_full  el_before_av_one_half  first no_margin flex_column_table_cell av-equal-height-column av-align-middle  column-top-margin'     ><style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-4u7wyx-0f061107308905902b309225d4d48956\">\n#top .av-special-heading.av-4u7wyx-0f061107308905902b309225d4d48956{\npadding-bottom:0;\ncolor:#ffffff;\nfont-size:22px;\n}\nbody .av-special-heading.av-4u7wyx-0f061107308905902b309225d4d48956 .av-special-heading-tag .heading-char{\nfont-size:25px;\n}\n#top #wrap_all .av-special-heading.av-4u7wyx-0f061107308905902b309225d4d48956 .av-special-heading-tag{\nfont-size:22px;\n}\n.av-special-heading.av-4u7wyx-0f061107308905902b309225d4d48956 .special-heading-inner-border{\nborder-color:#ffffff;\n}\n.av-special-heading.av-4u7wyx-0f061107308905902b309225d4d48956 .av-subheading{\nfont-size:15px;\n}\n\n@media only screen and (min-width: 480px) and (max-width: 767px){ \n#top #wrap_all .av-special-heading.av-4u7wyx-0f061107308905902b309225d4d48956 .av-special-heading-tag{\nfont-size:0.8em;\n}\n}\n\n@media only screen and (max-width: 479px){ \n#top #wrap_all .av-special-heading.av-4u7wyx-0f061107308905902b309225d4d48956 .av-special-heading-tag{\nfont-size:0.8em;\n}\n}\n<\/style>\n<div  class='av-special-heading av-4u7wyx-0f061107308905902b309225d4d48956 av-special-heading-h3 custom-color-heading blockquote modern-quote  avia-builder-el-4  avia-builder-el-no-sibling  av-inherit-size'><h3 class='av-special-heading-tag '  itemprop=\"headline\"  ><span style=\"font-style: italic;\"><span class='special_amp'>&#8222;<\/span>A colonic transit test with radiopaque markers is a very useful test to provide objective confirmation of a patient\u00b4s subjective complaint of altered frequency of defecation<span class='special_amp'>&#8221;<\/span><\/span><\/h3><div class='av_custom_color av-subheading av-subheading_below'><p><span style=\"display: inline-block; margin-top: 10px;\">(Keighley et al., 2018).<\/span><\/p>\n<\/div><div class=\"special-heading-border\"><div class=\"special-heading-inner-border\"><\/div><\/div><\/div><\/div>\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-22yqpl-03bfba57936aa821192e6534743fd232\">\n.flex_column.av-22yqpl-03bfba57936aa821192e6534743fd232{\nheight:auto;\nmin-height:300px;\nbackground:url(https:\/\/medifactia.com\/pl\/wp-content\/uploads\/sites\/12\/2023\/07\/medifactia-TP-Infinit.jpg) 50% 50% no-repeat scroll ;\n}\n<\/style>\n<div  class='flex_column av-22yqpl-03bfba57936aa821192e6534743fd232 av_one_half  avia-builder-el-5  el_after_av_one_half  el_before_av_hr  no_margin flex_column_table_cell av-equal-height-column av-align-middle avia-full-stretch  column-top-margin'     ><\/div><\/div><!--close column table wrapper. Autoclose: 1 -->\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-legvqv70-90b55503b340256b0efcbb3200fd03e7\">\n#top .hr.hr-invisible.av-legvqv70-90b55503b340256b0efcbb3200fd03e7{\nheight:50px;\n}\n<\/style>\n<div  class='hr av-legvqv70-90b55503b340256b0efcbb3200fd03e7 hr-invisible  avia-builder-el-6  el_after_av_one_half  el_before_av_one_full '><span class='hr-inner '><span class=\"hr-inner-style\"><\/span><\/span><\/div>\n<div  class='flex_column av-8j1ibd-f988b7c1e94eb26503b43f64a31f2b4d av_one_full  avia-builder-el-7  el_after_av_hr  el_before_av_one_full  first flex_column_div  '     ><p>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-k8sj8lnh-5984e24f31cb020d96947ae787996426\">\n#top .av-special-heading.av-k8sj8lnh-5984e24f31cb020d96947ae787996426{\npadding-bottom:20px;\n}\nbody .av-special-heading.av-k8sj8lnh-5984e24f31cb020d96947ae787996426 .av-special-heading-tag .heading-char{\nfont-size:25px;\n}\n.av-special-heading.av-k8sj8lnh-5984e24f31cb020d96947ae787996426 .av-subheading{\nfont-size:15px;\n}\n<\/style>\n<div  class='av-special-heading av-k8sj8lnh-5984e24f31cb020d96947ae787996426 av-special-heading-h2 blockquote modern-quote  avia-builder-el-8  el_before_av_textblock  avia-builder-el-first '><h2 class='av-special-heading-tag '  itemprop=\"headline\"  >The Transit-Pellets method can measure rapid, normal and slow colonic transit<\/h2><div class=\"special-heading-border\"><div class=\"special-heading-inner-border\"><\/div><\/div><\/div><br \/>\n<section  class='av_textblock_section av-k2u6leet-5ecc55806cd8678d0147b6b2e6ce56f2 '   itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock'  itemprop=\"text\" ><p>Given that the X-ray on day 7 after ingestion of 10 markers daily for six days is performed in the saturation state, i.e. that the number of retained markers is in the interval 3-55 markers, the CTT can be given in numerical values, e.g., in days with one decimal. The corresponding CTT will be 0.3 \u2013 5.5 days. Since the reference values (percentiles 5 \u2013 95) for healthy women is 0.6 \u2013 4.0 days and in men 0.5 \u2013 2.2 days, the whole spectrum from rapid to slow transit values can be numerically calculated. <sup>1<\/sup><\/p>\n<p>If saturation has not been achieved, i.e., as a mean less than half of the first marker dose has been excreted (&gt; 55 markers retained) CTT is set to &gt; 5.5 days for that subject. Otherwise, CTT might be underestimated.<\/p>\n<p>If the saturation state has passed, i.e. less than half of the last marker dose (0-2 markers) is retained the CTT is set to &lt; 0.3 days. The capability of the Transit-Pellets method to yield numerical values for rapid, normal as well as slow CTT is unique among CTT radiopaque marker methods used in clinical practice. The daily dose of markers used, 10 daily, gives accuracy in CTT close to that with 20 markers daily, and sufficient for use in clinical practice and in scientific studies. <sup>2<\/sup><\/p>\n<\/div><\/section><\/p><\/div>\n<div  class='flex_column av-7z7cft-a6f887bb9224a4d225ad15959a7307ef av_one_full  avia-builder-el-10  el_after_av_one_full  el_before_av_one_full  first flex_column_div  column-top-margin'     ><p>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-ld4j0wg0-620710411ec6dbf43ce964d3c40de371\">\n#top .av-special-heading.av-ld4j0wg0-620710411ec6dbf43ce964d3c40de371{\npadding-bottom:20px;\n}\nbody .av-special-heading.av-ld4j0wg0-620710411ec6dbf43ce964d3c40de371 .av-special-heading-tag .heading-char{\nfont-size:25px;\n}\n.av-special-heading.av-ld4j0wg0-620710411ec6dbf43ce964d3c40de371 .av-subheading{\nfont-size:15px;\n}\n<\/style>\n<div  class='av-special-heading av-ld4j0wg0-620710411ec6dbf43ce964d3c40de371 av-special-heading-h2 blockquote modern-quote  avia-builder-el-11  el_before_av_textblock  avia-builder-el-first '><h2 class='av-special-heading-tag '  itemprop=\"headline\"  >The Transit-Pellets method can differentiate between slow transit and normal transit constipation<\/h2><div class=\"special-heading-border\"><div class=\"special-heading-inner-border\"><\/div><\/div><\/div><br \/>\n<section  class='av_textblock_section av-ld4j1aa3-46a46ee791421f1ab5420e191e9271e2 '   itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock'  itemprop=\"text\" ><p>Measurements with the Transit-Pellets method show that patients suffering from constipation have CTT either in the normal CTT range or delayed transit time above the reference range.<sup>3, 4, 5<\/sup> In studies of patients with constipation the proportion of slow transit was 50% in functional constipation,<sup>3<\/sup> 15% in IBS related constipation,<sup>4<\/sup> and 46% in mixed functional and IBS related constipation.<sup>5<\/sup> With the differentiation shown with the Transit-Pellets method between slow and normal transit constipation it could be demonstrated that the metabolism of bile acids, important for colonic function, is disturbed in patients with slow transit constipation.<sup>5<\/sup><\/p>\n<\/div><\/section><\/p><\/div>\n<div  class='flex_column av-5fk3ah-671d433fdd3877617f7e58eb17686acd av_one_full  avia-builder-el-13  el_after_av_one_full  el_before_av_one_full  first flex_column_div  column-top-margin'     ><p>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-ld4j1pme-141736349b6a1294c6b8b214f9feabbf\">\n#top .av-special-heading.av-ld4j1pme-141736349b6a1294c6b8b214f9feabbf{\npadding-bottom:20px;\n}\nbody .av-special-heading.av-ld4j1pme-141736349b6a1294c6b8b214f9feabbf .av-special-heading-tag .heading-char{\nfont-size:25px;\n}\n.av-special-heading.av-ld4j1pme-141736349b6a1294c6b8b214f9feabbf .av-subheading{\nfont-size:15px;\n}\n<\/style>\n<div  class='av-special-heading av-ld4j1pme-141736349b6a1294c6b8b214f9feabbf av-special-heading-h2 blockquote modern-quote  avia-builder-el-14  el_before_av_textblock  avia-builder-el-first '><h2 class='av-special-heading-tag '  itemprop=\"headline\"  >The Transit-Pellets method can identify segmental colon dysfunction in patients with constipation<\/h2><div class=\"special-heading-border\"><div class=\"special-heading-inner-border\"><\/div><\/div><\/div><br \/>\n<section  class='av_textblock_section av-ld4j2ajr-95ede2cef24998d1cbc4cce11e9ec7a0 '   itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock'  itemprop=\"text\" ><p>Transit times in the different segments of colon (ascendent, transverse, descendent and rectosigmoid part) can be measured with the Transit-Pellets method by applying to the segments similar criteria for saturation as used for total CTT. Thus, a numerical value for the transit can be given for segments provided that at least half of a daily dose (5 markers) has passed that segment.<\/p>\n<p>In patients with constipation the Transit-Pellets method can diagnose segmental dysfunction as a delay (increased transit time) in the segment in question. Thus, outlet obstruction is seen as a delay in rectosigmoid transit time.<sup>3<\/sup> The serious constipation disorder colonic inertia is identified with a delayed total CTT and prolonged transit time (&gt;1.5 days) in the ascendant part of colon.<sup>3<\/sup> This identification is clinically important since surgical treatment with colectomy for constipation usually is contraindicated and should only be considered in very selected case if transit is clearly delayed in the right colon.<\/p>\n<\/div><\/section><\/p><\/div>\n<div  class='flex_column av-h6mg9-936bea33905ccc7b1ce28d6adce83d3e av_one_full  avia-builder-el-16  el_after_av_one_full  el_before_av_one_full  first flex_column_div  column-top-margin'     ><p>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-1x1h8p-12b3274f9876c1aa8c3f0d74d22d1d6c\">\n#top .av-special-heading.av-1x1h8p-12b3274f9876c1aa8c3f0d74d22d1d6c{\npadding-bottom:20px;\n}\nbody .av-special-heading.av-1x1h8p-12b3274f9876c1aa8c3f0d74d22d1d6c .av-special-heading-tag .heading-char{\nfont-size:25px;\n}\n.av-special-heading.av-1x1h8p-12b3274f9876c1aa8c3f0d74d22d1d6c .av-subheading{\nfont-size:15px;\n}\n<\/style>\n<div  class='av-special-heading av-1x1h8p-12b3274f9876c1aa8c3f0d74d22d1d6c av-special-heading-h2 blockquote modern-quote  avia-builder-el-17  el_before_av_textblock  avia-builder-el-first '><h2 class='av-special-heading-tag '  itemprop=\"headline\"  >The Transit-Pellets method can differentiate between normal and rapid transit diarrhoea<\/h2><div class=\"special-heading-border\"><div class=\"special-heading-inner-border\"><\/div><\/div><\/div><br \/>\n<section  class='av_textblock_section av-ld4j3675-7e2673c4137c490b4434b68f7861aeb9 '   itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock'  itemprop=\"text\" ><p>The short interval between marker intake and X-ray with the Transit-Pellets method enables investigation of rapid colonic transit in patients with long-lasting diarrhoea. Chronic diarrhoea caused by bile acids (so called IBAM, idiopathic bile acid malabsorption or IBAD, bile acid diarrhoea) is much more common than previously believed. In patients with bile acid diarrhoea CTT is usually markedly decreased. 50% of males and 75% of females with IBAM have rapid CTT. IBAM is a very unlikely diagnose if CTT is &gt;1.1 day in men and &gt;1.5 day in women. In a similar way segmental rectosigmoid transit time is markedly decreased in both men and women with this disorder. A normal rectosigmoid transit time speaks strongly against an IBAM\/IBAD diagnose.<sup>6<\/sup><\/p>\n<p>For the functional disorder IBS with diarrhoea (IBS-D) the Transit-Pellets method differentiates between normal and rapid transit diarrhoea. Thus, in 126 patients with IBS-D, 27% had rapid CTT.<sup>4<\/sup> The finding of rapid transit in patients with diarrhoea assists in selecting treatment aimed to slow down colonic transit.<\/p>\n<\/div><\/section><\/p><\/div>\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-4hj3byh-f9cea495257f94041f713c28c76f9385\">\n.flex_column.av-4hj3byh-f9cea495257f94041f713c28c76f9385{\nborder-radius:0px 0px 0px 0px;\npadding:0px 0px 0px 0px;\n}\n<\/style>\n<div  class='flex_column av-4hj3byh-f9cea495257f94041f713c28c76f9385 av_one_full  avia-builder-el-19  el_after_av_one_full  el_before_av_hr  first flex_column_div av-zero-column-padding  column-top-margin'     ><p>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-ld4j2ltv-f6be2a3fa70eee74370f068cfcdcd9a1\">\n#top .av-special-heading.av-ld4j2ltv-f6be2a3fa70eee74370f068cfcdcd9a1{\npadding-bottom:20px;\n}\nbody .av-special-heading.av-ld4j2ltv-f6be2a3fa70eee74370f068cfcdcd9a1 .av-special-heading-tag .heading-char{\nfont-size:25px;\n}\n.av-special-heading.av-ld4j2ltv-f6be2a3fa70eee74370f068cfcdcd9a1 .av-subheading{\nfont-size:15px;\n}\n<\/style>\n<div  class='av-special-heading av-ld4j2ltv-f6be2a3fa70eee74370f068cfcdcd9a1 av-special-heading-h2 blockquote modern-quote  avia-builder-el-20  el_before_av_textblock  avia-builder-el-first '><h2 class='av-special-heading-tag '  itemprop=\"headline\"  >The Transit-Pellets method can identify treatment effects in patients with chronic constipation<\/h2><div class=\"special-heading-border\"><div class=\"special-heading-inner-border\"><\/div><\/div><\/div><br \/>\n<section  class='av_textblock_section av-ld4j3s53-6950aa5b569304af4dd90371c77c812c '   itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock'  itemprop=\"text\" ><p>The single X-ray Transit-Pellets method with low radiation dose is suitable when repeated CTT measurements are wanted. Therefore, the method has been used to follow treatment effects on both total and segmental colonic transit in constipation.<\/p>\n<p>The IBAT inhibitor elobixibat (A3309) was studied in 30 patients with chronic idiopathic constipation, treatment dose 0.1-10 mg\/day. The Transit-Pellets method demonstrated an accelerating effect on CTT, particularly with the highest dose. CTT was reduced by 57% and it was shown that the effect was on the segments from the transverse to the rectosigmoid part where the transit time reduction was 1.7 days.<sup>7<\/sup> Thus, at treatment of constipation the Transit-Pellets method can show both an overall effect on CTT and an effect on the target region in the colon.<\/p>\n<\/div><\/section><\/p><\/div>\n<div  class='hr av-4mdmxl-d91eb7528cac8f9843585a5c3abd4e42 hr-default  avia-builder-el-22  el_after_av_one_full  el_before_av_one_full '><span class='hr-inner '><span class=\"hr-inner-style\"><\/span><\/span><\/div>\n<div  class='flex_column av-1zksa1-184d9768188b1305d6074b8a7a90838f av_one_full  avia-builder-el-23  el_after_av_hr  avia-builder-el-last  sources first flex_column_div  '     ><style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-ldd51dyk-5abf2e0ef2118dbbd81cf46fd7702e09\">\n#top .av_textblock_section.av-ldd51dyk-5abf2e0ef2118dbbd81cf46fd7702e09 .avia_textblock{\nfont-size:12px;\ncolor:#707070;\n}\n<\/style>\n<section  class='av_textblock_section av-ldd51dyk-5abf2e0ef2118dbbd81cf46fd7702e09 '   itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock av_inherit_color'  itemprop=\"text\" ><ol>\n<li>Sadik, R., Abrahamsson, H., Stotzer, P.O. (2003). Gender differences in gut transit shown with a newly developed radiological procedure. Scand. J. Gastroenterol., Vol. 38, 36-42.<\/li>\n<li>Abrahamsson, H. &amp; Antov, S. (2010). Accuracy in assessment of colonic transit time with particles: how many markers should be used? Neurogastroenterol Motil., Vol. 22, 1164-69.<\/li>\n<li>Abrahamsson, H., Antov, S., Bosaeus, I. (1988). Gastrointestinal and colonic transit time evaluated by a single abdominal X-ray in healthy subjects and constipated patients. Scand. J. Gastroenterol., Vol. 23 (suppl. 152), 72-80.<\/li>\n<li>T\u00f6rnblom, H., van Oudenhove, L., Sadik, R., Abrahamsson, H., Tack, J., Simr\u00e9n, M. (2012). Colonic transit time and IBS symptoms: what\u2019s the link? Am. J. Gastroenterol., Vol. 107(5), 754-60.<\/li>\n<li>Abrahamsson, H., Ostlund-Lindqvist, A.M., Nilsson, R., Simr\u00e9n, M., Gillberg, P.G. (2008). Altered bile acid metabolism patients with constipation-predominant irritable bowel syndrome and functional constipation. Scand J Gastroenterol., Vol. 43(12), 1483-8.<\/li>\n<li>Sadik, R., Abrahamsson, H., Ung, K.A., et al. (2004). Accelerating regional bowel transit and overweight shown in idiopathic bile acid malabsorption. Am. J. Gastroenterol., Vol. 99, 711-718.<\/li>\n<li>Simr\u00e9n, M., Bajor, A., Gillberg, PG., Rudling, M., Abrahamsson, H. (2011). Randomised clinical trial: The ileal bile acid transporter inhibitor A3309 vs. placebo in patients with chronic idiopathic constipation-a double-blind study. Aliment Pharmacol Ther., Vol. 34(1), 41-50.<\/li>\n<\/ol>\n<\/div><\/section><\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-15060","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/medifactia.com\/pl\/wp-json\/wp\/v2\/pages\/15060","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medifactia.com\/pl\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/medifactia.com\/pl\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/medifactia.com\/pl\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/medifactia.com\/pl\/wp-json\/wp\/v2\/comments?post=15060"}],"version-history":[{"count":3,"href":"https:\/\/medifactia.com\/pl\/wp-json\/wp\/v2\/pages\/15060\/revisions"}],"predecessor-version":[{"id":15147,"href":"https:\/\/medifactia.com\/pl\/wp-json\/wp\/v2\/pages\/15060\/revisions\/15147"}],"wp:attachment":[{"href":"https:\/\/medifactia.com\/pl\/wp-json\/wp\/v2\/media?parent=15060"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}