{"id":15055,"date":"2023-01-19T09:22:32","date_gmt":"2023-01-19T08:22:32","guid":{"rendered":"https:\/\/medifactia.com\/pl\/clinical-guidance\/"},"modified":"2026-02-11T13:31:07","modified_gmt":"2026-02-11T12:31:07","slug":"clinical-guidance","status":"publish","type":"page","link":"https:\/\/medifactia.com\/pl\/clinical-guidance\/","title":{"rendered":"Clinical Guidance"},"content":{"rendered":"<div  class='flex_column av-m86wis-2d8223e62eb25091d7008c45a0392f83 av_one_full  avia-builder-el-0  el_before_av_one_full  avia-builder-el-first  first flex_column_div  '     ><style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-ayp0k-360182483236960f3667ee40093f0447\">\n.avia-image-container.av-ayp0k-360182483236960f3667ee40093f0447 img.avia_image{\nbox-shadow:none;\n}\n.avia-image-container.av-ayp0k-360182483236960f3667ee40093f0447 .av-image-caption-overlay-center{\ncolor:#ffffff;\n}\n<\/style>\n<div  class='avia-image-container av-ayp0k-360182483236960f3667ee40093f0447 av-styling- avia-align-center  avia-builder-el-1  avia-builder-el-no-sibling '   itemprop=\"image\" itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/ImageObject\" ><div class=\"avia-image-container-inner\"><div class=\"avia-image-overlay-wrap\"><img decoding=\"async\" fetchpriority=\"high\" class='wp-image- avia-img-lazy-loading-not- avia_image ' src=\"https:\/\/medifactia.com\/us\/wp-content\/uploads\/sites\/2\/2023\/02\/medifactia-lakare.jpg\" alt='' title=''   itemprop=\"thumbnailUrl\"  \/><\/div><\/div><\/div><\/div>\n<div  class='flex_column av-2pflgtg-79b2ddf23b9e62e76f5c9bb3e9042294 av_one_full  avia-builder-el-2  el_after_av_one_full  el_before_av_one_half  first flex_column_div  column-top-margin'     ><p>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-ld2w114u-c2f8a25abbff96cb0e5c9ca895292563\">\n#top .av-special-heading.av-ld2w114u-c2f8a25abbff96cb0e5c9ca895292563{\npadding-bottom:10px;\n}\nbody .av-special-heading.av-ld2w114u-c2f8a25abbff96cb0e5c9ca895292563 .av-special-heading-tag .heading-char{\nfont-size:25px;\n}\n.av-special-heading.av-ld2w114u-c2f8a25abbff96cb0e5c9ca895292563 .av-subheading{\nfont-size:15px;\n}\n<\/style>\n<div  class='av-special-heading av-ld2w114u-c2f8a25abbff96cb0e5c9ca895292563 av-special-heading-h1 blockquote modern-quote  avia-builder-el-3  el_before_av_textblock  avia-builder-el-first '><h1 class='av-special-heading-tag '  itemprop=\"headline\"  >Clinical Guidance for Healthcare Professionals<\/h1><div class=\"special-heading-border\"><div class=\"special-heading-inner-border\"><\/div><\/div><\/div><br \/>\n<section  class='av_textblock_section av-ld2w20rf-78212072244fb57d900d1e76fb57fd7c '   itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock'  itemprop=\"text\" ><p>A radiopaque marker study with Transit-Pellets is recommended for clinical evaluation of colonic transit time (CTT) in patients with constipation and irritable bowel syndrome (IBS). The test is indicated to differentiate between normal and slow transit, to assess segmental transit times in patients with delayed total colon transit and to assists in the evaluation of unexplained chronic diarrhoea.<sup>1<\/sup><\/p>\n<p>The Transit-Pellets method, also known as the Abrahamsson method, offers a valuable alternative for measuring colonic transit time in patients, as it allows for quantification of CTT while minimizing exposure to radiation. This method is unique in that it is the only single X-ray approach that addresses a range of practical considerations, such as gender-specific differences, both rapid and slow CTT, and the ability to locate dysfunction in various segments of the colon. By achieving an equilibrium between daily marker input and output, this method provides accurate and reliable numerical values for CTT.<sup>2<\/sup><\/p>\n<\/div><\/section><\/p><\/div>\n<div  class='flex_column av-1m8bkh0-b6b6de2c84439939cd6696089c43598e av_one_half  avia-builder-el-5  el_after_av_one_full  el_before_av_one_fourth  first flex_column_div  column-top-margin'     ><section  class='av_textblock_section av-ldk2lhgk-84d7d4321a2d9253bac387139cab5109 '   itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock'  itemprop=\"text\" ><p>The Transit-Pellets method and Transit-Pellets device can be used to measure:<\/p>\n<ul>\n<li>Total colonic transit time (in days or hours);<\/li>\n<li>Segmental transit time;<\/li>\n<li>Transit time in proximal colon (e.g., in colonic inertia);<\/li>\n<li>Rapid colonic transit<\/li>\n<\/ul>\n<\/div><\/section><\/div>\n<div  class='flex_column av-16d6fus-38d950c2e4046492d7c97480c878eff8 av_one_fourth  avia-builder-el-7  el_after_av_one_half  el_before_av_one_fourth  flex_column_div  column-top-margin'     ><style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-ldk2kw5u-b922849dec82d8772c1f8d11130ecef9\">\n.avia-image-container.av-ldk2kw5u-b922849dec82d8772c1f8d11130ecef9 img.avia_image{\nbox-shadow:none;\n}\n.avia-image-container.av-ldk2kw5u-b922849dec82d8772c1f8d11130ecef9 .av-image-caption-overlay-center{\ncolor:#ffffff;\n}\n<\/style>\n<div  class='avia-image-container av-ldk2kw5u-b922849dec82d8772c1f8d11130ecef9 av-styling- avia-align-center  avia-builder-el-8  avia-builder-el-no-sibling '   itemprop=\"image\" itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/ImageObject\" ><div class=\"avia-image-container-inner\"><div class=\"avia-image-overlay-wrap\"><img decoding=\"async\" fetchpriority=\"high\" class='wp-image-14211 avia-img-lazy-loading-not-14211 avia_image ' src=\"https:\/\/medifactia.com\/pl\/wp-content\/uploads\/sites\/12\/2021\/04\/Rapid-transit.png\" alt='' title='Rapid-transit'  height=\"1200\" width=\"840\"  itemprop=\"thumbnailUrl\" srcset=\"https:\/\/medifactia.com\/pl\/wp-content\/uploads\/sites\/12\/2021\/04\/Rapid-transit.png 840w, https:\/\/medifactia.com\/pl\/wp-content\/uploads\/sites\/12\/2021\/04\/Rapid-transit-210x300.png 210w, https:\/\/medifactia.com\/pl\/wp-content\/uploads\/sites\/12\/2021\/04\/Rapid-transit-721x1030.png 721w, https:\/\/medifactia.com\/pl\/wp-content\/uploads\/sites\/12\/2021\/04\/Rapid-transit-768x1097.png 768w, https:\/\/medifactia.com\/pl\/wp-content\/uploads\/sites\/12\/2021\/04\/Rapid-transit-494x705.png 494w\" sizes=\"(max-width: 840px) 100vw, 840px\" \/><\/div><\/div><\/div><\/div>\n<div  class='flex_column av-mhpu78-9bcc2e1241802d73d7f9b8f52424b430 av_one_fourth  avia-builder-el-9  el_after_av_one_fourth  el_before_av_one_full  flex_column_div  column-top-margin'     ><style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-ldk2ji69-5ec2f711133591f71e167adf7ae46fcf\">\n.avia-image-container.av-ldk2ji69-5ec2f711133591f71e167adf7ae46fcf img.avia_image{\nbox-shadow:none;\n}\n.avia-image-container.av-ldk2ji69-5ec2f711133591f71e167adf7ae46fcf .av-image-caption-overlay-center{\ncolor:#ffffff;\n}\n<\/style>\n<div  class='avia-image-container av-ldk2ji69-5ec2f711133591f71e167adf7ae46fcf av-styling- avia-align-center  avia-builder-el-10  avia-builder-el-no-sibling '   itemprop=\"image\" itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/ImageObject\" ><div class=\"avia-image-container-inner\"><div class=\"avia-image-overlay-wrap\"><img decoding=\"async\" fetchpriority=\"high\" class='wp-image-14212 avia-img-lazy-loading-not-14212 avia_image ' src=\"https:\/\/medifactia.com\/pl\/wp-content\/uploads\/sites\/12\/2021\/04\/Slow-transit.png\" alt='' title='Slow-transit'  height=\"1200\" width=\"825\"  itemprop=\"thumbnailUrl\" srcset=\"https:\/\/medifactia.com\/pl\/wp-content\/uploads\/sites\/12\/2021\/04\/Slow-transit.png 825w, https:\/\/medifactia.com\/pl\/wp-content\/uploads\/sites\/12\/2021\/04\/Slow-transit-206x300.png 206w, https:\/\/medifactia.com\/pl\/wp-content\/uploads\/sites\/12\/2021\/04\/Slow-transit-708x1030.png 708w, https:\/\/medifactia.com\/pl\/wp-content\/uploads\/sites\/12\/2021\/04\/Slow-transit-768x1117.png 768w, https:\/\/medifactia.com\/pl\/wp-content\/uploads\/sites\/12\/2021\/04\/Slow-transit-485x705.png 485w\" sizes=\"(max-width: 825px) 100vw, 825px\" \/><\/div><\/div><\/div><\/div>\n<div  class='flex_column av-wivdr8-3183832b97e55369700a3e55bc4afb6e av_one_full  avia-builder-el-11  el_after_av_one_fourth  el_before_av_one_full  first flex_column_div  column-top-margin'     ><p>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-ldk2o5je-c58560950992a3dd8478917f528cadd0\">\n#top .hr.hr-invisible.av-ldk2o5je-c58560950992a3dd8478917f528cadd0{\nmargin-top:-30px;\nheight:1px;\n}\n<\/style>\n<div  class='hr av-ldk2o5je-c58560950992a3dd8478917f528cadd0 hr-invisible  avia-builder-el-12  el_before_av_textblock  avia-builder-el-first '><span class='hr-inner '><span class=\"hr-inner-style\"><\/span><\/span><\/div><br \/>\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-ldk2nc9g-a245d7e3f0f37909ceb50077ccf69a5b\">\n#top .av_textblock_section.av-ldk2nc9g-a245d7e3f0f37909ceb50077ccf69a5b .avia_textblock{\nfont-size:12px;\n}\n<\/style>\n<section  class='av_textblock_section av-ldk2nc9g-a245d7e3f0f37909ceb50077ccf69a5b '   itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock'  itemprop=\"text\" ><p style=\"text-align: right;\"><em>Illustration of Transit-Pellets marker movement<\/em><\/p>\n<\/div><\/section><\/p><\/div>\n<div  class='flex_column av-1yk8d44-5fe3c72024caf27955ffb822163e7dca av_one_full  avia-builder-el-14  el_after_av_one_full  el_before_av_one_full  first flex_column_div  column-top-margin'     ><p>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-ld2w2blk-beebb3b8bb709c6e22a93e6d44d35adc\">\n#top .av-special-heading.av-ld2w2blk-beebb3b8bb709c6e22a93e6d44d35adc{\npadding-bottom:10px;\n}\nbody .av-special-heading.av-ld2w2blk-beebb3b8bb709c6e22a93e6d44d35adc .av-special-heading-tag .heading-char{\nfont-size:25px;\n}\n.av-special-heading.av-ld2w2blk-beebb3b8bb709c6e22a93e6d44d35adc .av-subheading{\nfont-size:15px;\n}\n<\/style>\n<div  class='av-special-heading av-ld2w2blk-beebb3b8bb709c6e22a93e6d44d35adc av-special-heading-h2 blockquote modern-quote  avia-builder-el-15  el_before_av_textblock  avia-builder-el-first '><h2 class='av-special-heading-tag '  itemprop=\"headline\"  >From Diet, Laxatives and Lifestyle Modifications to Colonic Transit Studies<\/h2><div class=\"special-heading-border\"><div class=\"special-heading-inner-border\"><\/div><\/div><\/div><br \/>\n<section  class='av_textblock_section av-ld2w3p18-89d8c764203ab10a518f69a4d5b40baa '   itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock'  itemprop=\"text\" ><p>The principles for determining the timing of colonic transit time measurements in relation to treatment steps may vary based on the specific center and the individual physician\u00b4s experience. In general, the initial management approach for constipation includes focusing on diet and lifestyle modifications, as well as utilizing standard over-the-counter laxatives such as bulking agents and non-absorbable carbohydrates. If these measures are ineffective, it is common to proceed with a colonic transit study with Transit-Pellets radiopaque markers. Some physicians may also try additional treatment methods, such as the use of saline laxatives or motility-stimulating drugs, before arranging for a colonic transit test with Transit-Pellets.<\/p>\n<p>The referral for the Transit-Pellets procedure may be initiated by a primary care physician or other physician with expertise in treating patients with gastrointestinal conditions. In instances where the case presents complexity or uncertainty, the referral may be directed directly to a gastroenterology specialist for further evaluation and assessment.<\/p>\n<p>Transit studies with the Transit-Pellets primarily address the question, <em>\u201cdoes the patient have normal or slow transit?\u201d<\/em>. Further, the assessment of segmental transit time is of paramount importance when evaluating patients with delayed transit. It is advisable that a request is made to the radiology department for the identification of which segment is abnormal.<\/p>\n<\/div><\/section><\/p><\/div>\n<div  class='flex_column av-1279hqr-0756d333a053417afa4e33d2af820d57 av_one_full  avia-builder-el-17  el_after_av_one_full  el_before_av_one_full  first flex_column_div  column-top-margin'     ><p>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-ld8nmu8t-9379645aab143a333189b319b7f4851f\">\n#top .av-special-heading.av-ld8nmu8t-9379645aab143a333189b319b7f4851f{\npadding-bottom:10px;\n}\nbody .av-special-heading.av-ld8nmu8t-9379645aab143a333189b319b7f4851f .av-special-heading-tag .heading-char{\nfont-size:25px;\n}\n.av-special-heading.av-ld8nmu8t-9379645aab143a333189b319b7f4851f .av-subheading{\nfont-size:15px;\n}\n<\/style>\n<div  class='av-special-heading av-ld8nmu8t-9379645aab143a333189b319b7f4851f av-special-heading-h3 blockquote modern-quote  avia-builder-el-18  el_before_av_image  avia-builder-el-first '><h3 class='av-special-heading-tag '  itemprop=\"headline\"  >Clinical Decision Support Tool \u2013 Chronic Idiopathic Constipation <sup>3, 4<\/sup> <\/h3><div class=\"special-heading-border\"><div class=\"special-heading-inner-border\"><\/div><\/div><\/div><br \/>\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-ljmk50w7-f6642eb2baf6a7991c1aa4a292490665\">\n.avia-image-container.av-ljmk50w7-f6642eb2baf6a7991c1aa4a292490665 img.avia_image{\nbox-shadow:none;\n}\n.avia-image-container.av-ljmk50w7-f6642eb2baf6a7991c1aa4a292490665 .av-image-caption-overlay-center{\ncolor:#ffffff;\n}\n<\/style>\n<div  class='avia-image-container av-ljmk50w7-f6642eb2baf6a7991c1aa4a292490665 av-styling- av-img-linked avia-align-center  avia-builder-el-19  el_after_av_heading  el_before_av_textblock '   itemprop=\"image\" itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/ImageObject\" ><div class=\"avia-image-container-inner\"><div class=\"avia-image-overlay-wrap\"><a href=\"https:\/\/medifactia.com\/wp-content\/uploads\/2024\/11\/MM-23-005-Clinical-Decision-Support-Tool-CIC-ver02.pdf\" class='avia_image '  target=\"_blank\"  rel=\"noopener noreferrer\" aria-label='MM 23-005 Clinical Decision Support Tool - CIC_without references ver02'><img decoding=\"async\" fetchpriority=\"high\" class='wp-image-15167 avia-img-lazy-loading-not-15167 avia_image ' src=\"https:\/\/medifactia.com\/pl\/wp-content\/uploads\/sites\/12\/2024\/10\/MM-23-005-Clinical-Decision-Support-Tool-CIC_without-references-ver02.png\" alt='' title='MM 23-005 Clinical Decision Support Tool - CIC_without references ver02'  height=\"1809\" width=\"2560\"  itemprop=\"thumbnailUrl\" srcset=\"https:\/\/medifactia.com\/pl\/wp-content\/uploads\/sites\/12\/2024\/10\/MM-23-005-Clinical-Decision-Support-Tool-CIC_without-references-ver02.png 2560w, https:\/\/medifactia.com\/pl\/wp-content\/uploads\/sites\/12\/2024\/10\/MM-23-005-Clinical-Decision-Support-Tool-CIC_without-references-ver02-300x212.png 300w, https:\/\/medifactia.com\/pl\/wp-content\/uploads\/sites\/12\/2024\/10\/MM-23-005-Clinical-Decision-Support-Tool-CIC_without-references-ver02-1030x728.png 1030w, https:\/\/medifactia.com\/pl\/wp-content\/uploads\/sites\/12\/2024\/10\/MM-23-005-Clinical-Decision-Support-Tool-CIC_without-references-ver02-768x543.png 768w, https:\/\/medifactia.com\/pl\/wp-content\/uploads\/sites\/12\/2024\/10\/MM-23-005-Clinical-Decision-Support-Tool-CIC_without-references-ver02-1536x1086.png 1536w, https:\/\/medifactia.com\/pl\/wp-content\/uploads\/sites\/12\/2024\/10\/MM-23-005-Clinical-Decision-Support-Tool-CIC_without-references-ver02-2048x1447.png 2048w, https:\/\/medifactia.com\/pl\/wp-content\/uploads\/sites\/12\/2024\/10\/MM-23-005-Clinical-Decision-Support-Tool-CIC_without-references-ver02-1500x1060.png 1500w, https:\/\/medifactia.com\/pl\/wp-content\/uploads\/sites\/12\/2024\/10\/MM-23-005-Clinical-Decision-Support-Tool-CIC_without-references-ver02-260x185.png 260w, https:\/\/medifactia.com\/pl\/wp-content\/uploads\/sites\/12\/2024\/10\/MM-23-005-Clinical-Decision-Support-Tool-CIC_without-references-ver02-705x498.png 705w\" sizes=\"(max-width: 2560px) 100vw, 2560px\" \/><\/a><\/div><\/div><\/div><br \/>\n<section  class='av_textblock_section av-ljmkd8w8-32d8d17437ada7bb1b6953f41e57e2f2 '   itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock'  itemprop=\"text\" ><p>To download the Clinical Decision Tool for Irritable Bowel Syndrome (IBS), please click\u00a0<a class=\"popmake-15101\" href=\"#\">HERE<\/a>.<\/p>\n<\/div><\/section><\/p><\/div>\n<div  class='flex_column av-o04uw4-a584d42e2e436aa3e33182b758aab269 av_one_full  avia-builder-el-21  el_after_av_one_full  el_before_av_one_full  first flex_column_div  column-top-margin'     ><p>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-w8kl03-b619d834a11dbbfe802f00ed17965985\">\n#top .av-special-heading.av-w8kl03-b619d834a11dbbfe802f00ed17965985{\npadding-bottom:10px;\n}\nbody .av-special-heading.av-w8kl03-b619d834a11dbbfe802f00ed17965985 .av-special-heading-tag .heading-char{\nfont-size:25px;\n}\n.av-special-heading.av-w8kl03-b619d834a11dbbfe802f00ed17965985 .av-subheading{\nfont-size:15px;\n}\n<\/style>\n<div  class='av-special-heading av-w8kl03-b619d834a11dbbfe802f00ed17965985 av-special-heading-h2 blockquote modern-quote  avia-builder-el-22  el_before_av_textblock  avia-builder-el-first '><h2 class='av-special-heading-tag '  itemprop=\"headline\"  >A Step-by-Step Guide for Physicians and Radiologists<\/h2><div class=\"special-heading-border\"><div class=\"special-heading-inner-border\"><\/div><\/div><\/div><br \/>\n<section  class='av_textblock_section av-ld8nnx5g-6ff8444611e2ba05afce3a5c833eb3a2 '   itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock'  itemprop=\"text\" ><p>The Transit-Pellets radiopaque markers are prescribed by a physician for use by the patient in the home setting. The provision of clear instruction and information to the patient is a critical component of the procedure.<\/p>\n<p>Transit-Pellets come with an Instruction for Use (IFU) that is available in up to 20 languages. The IFU provides important instructions on the proper use of Transit-Pellets and should be thoroughly reviewed to ensure safe and effective use of the device. You will find it in the footer menu \u201cDownloads\u201d or you can enter it directly via <a href=\"https:\/\/medifactia.com\/wp-content\/uploads\/2026\/02\/0074-IFU-International-ver05.pdf\" target=\"_blank\" rel=\"noopener\">THIS LINK<\/a>.<\/p>\n<p>In the standard protocol, the X-ray department assumes responsibility for providing instruction and overseeing the use of the Transit-Pellets capsules. It is imperative that patients receive adequate instruction regarding the proper handling of the Transit-Pellets to ensure safe usage. In cases where assessment proves to be challenging, consultation with a gastroenterologist or a specialized gastrosurgeon may be sought for guidance.<\/p>\n<p>For further guidance on the appropriate utilization of the technique and Transit-Pellets capsules, refer to the <a href=\"https:\/\/medifactia.com\/wp-content\/uploads\/2023\/02\/0006EN-Clinical-Instruction-for-Use-ver06.pdf\" target=\"_blank\" rel=\"noopener\">Transit-Pellets Clinical Instruction for Use<\/a>. Please be aware that the Clinical Instruction for Use is subject to change. The most current version is always available on this site.<\/p>\n<\/div><\/section><\/p><\/div><div  class='flex_column av-1qaq24k-80804016cbf003f536786ba4ff1cdca4 av_one_full  avia-builder-el-24  el_after_av_one_full  el_before_av_one_full  first flex_column_div  column-top-margin'     ><p>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-146y2ys-8716f26968a2037bfe605337bf6ae0b0\">\n#top .av-special-heading.av-146y2ys-8716f26968a2037bfe605337bf6ae0b0{\npadding-bottom:10px;\n}\nbody .av-special-heading.av-146y2ys-8716f26968a2037bfe605337bf6ae0b0 .av-special-heading-tag .heading-char{\nfont-size:25px;\n}\n.av-special-heading.av-146y2ys-8716f26968a2037bfe605337bf6ae0b0 .av-subheading{\nfont-size:15px;\n}\n<\/style>\n<div  class='av-special-heading av-146y2ys-8716f26968a2037bfe605337bf6ae0b0 av-special-heading-h2 blockquote modern-quote  avia-builder-el-25  el_before_av_textblock  avia-builder-el-first '><h2 class='av-special-heading-tag '  itemprop=\"headline\"  >Instructions on Timing and Administration of Transit-Pellets Capsules<\/h2><div class=\"special-heading-border\"><div class=\"special-heading-inner-border\"><\/div><\/div><\/div><br \/>\n<section  class='av_textblock_section av-omzwis-fbceaab6cdebff9528b4d580510bc2d8 '   itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock'  itemprop=\"text\" ><p>The procedure for the colonic transit test using Transit-Pellets includes consuming ten radiopaque markers daily for a period of six days. The recommended time frame between the initial marker consumption and the X-ray examination on day seven is approximately 144 hours.<sup>1, 2<\/sup><\/p>\n<p>Advise the patient to follow the Transit-Pellets capsule regimen as detailed below:<br \/>\nOne capsule per day is to be consumed from day one through day five. On day six, the patient should consume one capsule labeled \u201c6:1\u201d in the morning and one capsule labeled \u201c6:2\u201d in the evening. Emphasize the importance of adherence to this schedule to the patient in order to obtain accurate results.<sup>1, 2<\/sup><\/p>\n<p><img decoding=\"async\" class=\"alignright size-full wp-image-15198\" style=\"margin-left: 25px;\" src=\"https:\/\/medifactia.com\/us\/wp-content\/uploads\/sites\/2\/2023\/02\/Transit-Pellets-Blister-gray.png\" alt=\"\" width=\"120\" \/>It\u00b4s also important that the capsules are taken at around the same time each day.<sup>1, 2<\/sup> For example, if the first capsule on day one is consumed at 8:00 am, the capsules on days two, three, four and five should also be taken around that same time. Additionally, on day six, the capsule labeled \u201c6:1\u201d should be consumed at approximately 8:00 am, while the capsule labeled \u201c6:2\u201d should be consumed around 8:00 pm the same day approximately 12 hours prior to the X-ray on day seven.<\/p>\n<p>For patients who may have difficulty swallowing capsules, an alternative method of ingestion can be employed. The contents of the capsules can be emptied into soft foods such as applesauce or yogurt and consumed in that form. It is important to note that the capsules and markers should not be chewed.<\/p>\n<\/div><\/section><\/p><\/div><\/p>\n<div  class='flex_column av-9ryiv50-30700fd60974c452beaedaf7f74205d6 av_one_full  avia-builder-el-27  el_after_av_one_full  el_before_av_one_full  first flex_column_div  column-top-margin'     ><p>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-ld2w6hog-349ce0a0ff541a28a3c355cc75761d10\">\n#top .av-special-heading.av-ld2w6hog-349ce0a0ff541a28a3c355cc75761d10{\npadding-bottom:10px;\n}\nbody .av-special-heading.av-ld2w6hog-349ce0a0ff541a28a3c355cc75761d10 .av-special-heading-tag .heading-char{\nfont-size:25px;\n}\n.av-special-heading.av-ld2w6hog-349ce0a0ff541a28a3c355cc75761d10 .av-subheading{\nfont-size:15px;\n}\n<\/style>\n<div  class='av-special-heading av-ld2w6hog-349ce0a0ff541a28a3c355cc75761d10 av-special-heading-h2 blockquote modern-quote  avia-builder-el-28  el_before_av_textblock  avia-builder-el-first '><h2 class='av-special-heading-tag '  itemprop=\"headline\"  >Schedule a Plain Abdominal Radiograph or a Fluoroscopy<\/h2><div class=\"special-heading-border\"><div class=\"special-heading-inner-border\"><\/div><\/div><\/div><br \/>\n<section  class='av_textblock_section av-ld2w7jab-1382c4f6393574e7adb3e540bcc4099b '   itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock'  itemprop=\"text\" ><p>The X-ray or fluoroscopy on day seven should be scheduled to take place about 12 hours after the patient\u00b4s last dose on the sixth day.<sup>1, 2<\/sup> Therefore, the time of the X-ray determines when the patient should take the Transit-Pellets capsules, both in terms of the day they should begin and the specific time they should take them. The following table provides a helpful reference:<\/p>\n<\/div><\/section><br \/>\n<div class='avia-data-table-wrap av-9kpr06c-dd9fb9ee66fcfbde76a4c840a98d4199 avia_responsive_table avia-table-1'><table  class='avia-table avia-data-table avia_pricing_default  avia-builder-el-30  el_after_av_textblock  el_before_av_textblock '  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/Table\" ><tbody><tr class='avia-heading-row'><th class=''>Day 1 (Swallow Capsule 1)<\/th><th class=''>Day 7 (Schedule X-ray)<\/th><\/tr><tr class=''><td class=''>Tuesday<\/td><td class=''>Monday<\/td><\/tr><tr class=''><td class=''>Wednesday<\/td><td class=''>Tuesday<\/td><\/tr><tr class=''><td class=''>Thursday<\/td><td class=''>Wednesday<\/td><\/tr><tr class=''><td class=''>Friday<\/td><td class=''>Thursday<\/td><\/tr><tr class=''><td class=''>Saturday<\/td><td class=''>Friday<\/td><\/tr><\/tbody><\/table><\/div><style type='text\/css'>.avia-table-1 td:nth-of-type(1):before { content: 'Day 1 (Swallow Capsule 1)'; } .avia-table-1 td:nth-of-type(2):before { content: 'Day 7 (Schedule X-ray)'; } <\/style><br \/>\n<section  class='av_textblock_section av-ld4gf1up-fba7acbab17b09a6ef11d4f1fd9736b8 '   itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock'  itemprop=\"text\" ><p>Adherence to the prescribed marker ingestion protocol is crucial for accurate results. However, a deviation of up to an hour in the timing of marker ingestion is permissible, but it is not recommended for clinics to routinely have patients ingest markers in the morning and then perform radiographic examinations later in the day, as this could lead to unreliable results.<\/p>\n<\/div><\/section><\/p><\/div>\n<div  class='flex_column av-2ucqdg-27bf3f03ae9418eb667d75f5b233e673 av_one_full  avia-builder-el-32  el_after_av_one_full  el_before_av_one_full  first flex_column_div  column-top-margin'     ><style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-26toixw-81201789a05f3433dac98a561dc49683\">\n.avia-image-container.av-26toixw-81201789a05f3433dac98a561dc49683 img.avia_image{\nbox-shadow:none;\n}\n.avia-image-container.av-26toixw-81201789a05f3433dac98a561dc49683 .av-image-caption-overlay-center{\ncolor:#ffffff;\n}\n<\/style>\n<div  class='avia-image-container av-26toixw-81201789a05f3433dac98a561dc49683 av-styling- avia-align-center  avia-builder-el-33  avia-builder-el-no-sibling '   itemprop=\"image\" itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/ImageObject\" ><div class=\"avia-image-container-inner\"><div class=\"avia-image-overlay-wrap\"><img decoding=\"async\" fetchpriority=\"high\" class='wp-image- avia-img-lazy-loading-not- avia_image ' src=\"https:\/\/medifactia.com\/us\/wp-content\/uploads\/sites\/2\/2023\/02\/Doctors-radiograph.jpg\" alt='' title=''   itemprop=\"thumbnailUrl\"  \/><\/div><\/div><\/div><\/div>\n<div  class='flex_column av-283rh5w-1258856a09cc57552bb2476f37dc589a av_one_full  avia-builder-el-34  el_after_av_one_full  el_before_av_hr  first flex_column_div  column-top-margin'     ><p>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-ld4gfmy1-04fce9108ff490465cf2fdb3782cac19\">\n#top .av-special-heading.av-ld4gfmy1-04fce9108ff490465cf2fdb3782cac19{\npadding-bottom:10px;\n}\nbody .av-special-heading.av-ld4gfmy1-04fce9108ff490465cf2fdb3782cac19 .av-special-heading-tag .heading-char{\nfont-size:25px;\n}\n.av-special-heading.av-ld4gfmy1-04fce9108ff490465cf2fdb3782cac19 .av-subheading{\nfont-size:15px;\n}\n<\/style>\n<div  class='av-special-heading av-ld4gfmy1-04fce9108ff490465cf2fdb3782cac19 av-special-heading-h3 blockquote modern-quote  avia-builder-el-35  el_before_av_textblock  avia-builder-el-first '><h3 class='av-special-heading-tag '  itemprop=\"headline\"  >Avoiding Laxatives During the Test: Importance for Accurate Results<\/h3><div class=\"special-heading-border\"><div class=\"special-heading-inner-border\"><\/div><\/div><\/div><br \/>\n<section  class='av_textblock_section av-ld4gfxr4-cee08f63952965b63c8818aec07178cb '   itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock'  itemprop=\"text\" ><p>For the duration of the test, it is important for patients to refrain from using laxatives. Further, while it may not always be feasible to avoid motility altering drugs, it is important to consider their potential impact when interpreting the test results.<sup>5<\/sup><\/p>\n<\/div><\/section><br \/>\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-ld4gg6ta-c3bbb778aee883523bc5c34a7d3de954\">\n#top .av-special-heading.av-ld4gg6ta-c3bbb778aee883523bc5c34a7d3de954{\npadding-bottom:10px;\n}\nbody .av-special-heading.av-ld4gg6ta-c3bbb778aee883523bc5c34a7d3de954 .av-special-heading-tag .heading-char{\nfont-size:25px;\n}\n.av-special-heading.av-ld4gg6ta-c3bbb778aee883523bc5c34a7d3de954 .av-subheading{\nfont-size:15px;\n}\n<\/style>\n<div  class='av-special-heading av-ld4gg6ta-c3bbb778aee883523bc5c34a7d3de954 av-special-heading-h3 blockquote modern-quote  avia-builder-el-37  el_after_av_textblock  el_before_av_textblock '><h3 class='av-special-heading-tag '  itemprop=\"headline\"  >What to Do if a Patient Misses a Transit-Pellets Capsule?<\/h3><div class=\"special-heading-border\"><div class=\"special-heading-inner-border\"><\/div><\/div><\/div><br \/>\n<section  class='av_textblock_section av-ld4ggmz7-43b7fc24ad5841f606c4fdb904ea720f '   itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock'  itemprop=\"text\" ><p>If a patient has missed a Transit-Pellets capsule, it is not recommended to compensate by taking a larger number of markers on a subsequent day. This is because the order of the patient\u00b4s transit time cannot be accurately determined, and it is therefore not possible to accurately assess the total and segmental colonic transit time using the markers. If a patient has missed the prescribed intake of markers on two occasions, it may be advisable to try again at a later time to ensure accurate results.<\/p>\n<\/div><\/section><br \/>\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-ld4ggwxq-7202a974010559f5e490482a7d7b495d\">\n#top .av-special-heading.av-ld4ggwxq-7202a974010559f5e490482a7d7b495d{\npadding-bottom:10px;\n}\nbody .av-special-heading.av-ld4ggwxq-7202a974010559f5e490482a7d7b495d .av-special-heading-tag .heading-char{\nfont-size:25px;\n}\n.av-special-heading.av-ld4ggwxq-7202a974010559f5e490482a7d7b495d .av-subheading{\nfont-size:15px;\n}\n<\/style>\n<div  class='av-special-heading av-ld4ggwxq-7202a974010559f5e490482a7d7b495d av-special-heading-h3 blockquote modern-quote  avia-builder-el-39  el_after_av_textblock  el_before_av_textblock '><h3 class='av-special-heading-tag '  itemprop=\"headline\"  >Carefully Selected Raw Materials<\/h3><div class=\"special-heading-border\"><div class=\"special-heading-inner-border\"><\/div><\/div><\/div><br \/>\n<section  class='av_textblock_section av-ld4gh7tg-ad2b3130be60e7061297ec771568bb56 '   itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock'  itemprop=\"text\" ><p>In contrast to other radiopaque markers available in the market, which are typically made of plasticized PVC (phthalates DEHP and DOP, and epoxidized soybean oil), Transit-Pellets are composed of 78% Elastosil \u00ae R 401\/60 Silicone Rubber and 22% Barium Sulphate.<\/p>\n<\/div><\/section><br \/>\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-ld8nri97-ba41a2e5fd2512af2ee0c194d94194c4\">\n#top .av-special-heading.av-ld8nri97-ba41a2e5fd2512af2ee0c194d94194c4{\npadding-bottom:10px;\n}\nbody .av-special-heading.av-ld8nri97-ba41a2e5fd2512af2ee0c194d94194c4 .av-special-heading-tag .heading-char{\nfont-size:25px;\n}\n.av-special-heading.av-ld8nri97-ba41a2e5fd2512af2ee0c194d94194c4 .av-subheading{\nfont-size:15px;\n}\n<\/style>\n<div  class='av-special-heading av-ld8nri97-ba41a2e5fd2512af2ee0c194d94194c4 av-special-heading-h3 blockquote modern-quote  avia-builder-el-41  el_after_av_textblock  el_before_av_textblock '><h3 class='av-special-heading-tag '  itemprop=\"headline\"  >Why 22% Barium Sulphate?<\/h3><div class=\"special-heading-border\"><div class=\"special-heading-inner-border\"><\/div><\/div><\/div><br \/>\n<section  class='av_textblock_section av-ld8nrzfb-087c3a3b44ed175a89b5d383181c7fb6 '   itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock'  itemprop=\"text\" ><p>International experts recommend using a 20-25% proportion of Barium Sulphate in Transit-Pellet markers to accurately measure colonic transit time.<sup>6<\/sup> Using a higher proportion of Barium Sulphate with a specific gravity (SG) above the recommended range of 1.2-1.7 for colonic contents (the dominating food residue cellulose has about 1.5), will lead to inaccurate results and will not yield the actual colonic transit time.<\/p>\n<\/div><\/section><\/p><\/div>\n<div  class='hr av-1c09eas-f26c1e08cbfd744d7b2e402bd146600e hr-default  avia-builder-el-43  el_after_av_one_full  el_before_av_one_full '><span class='hr-inner '><span class=\"hr-inner-style\"><\/span><\/span><\/div>\n<div  class='flex_column av-24iipw-37c524758052cf611645fba9b9681668 av_one_full  avia-builder-el-44  el_after_av_hr  avia-builder-el-last  sources first flex_column_div  '     ><style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-ldd5i53t-33da987ef19a9c0f592026043fcb3f11\">\n#top .av_textblock_section.av-ldd5i53t-33da987ef19a9c0f592026043fcb3f11 .avia_textblock{\nfont-size:12px;\ncolor:#707070;\n}\n<\/style>\n<section  class='av_textblock_section av-ldd5i53t-33da987ef19a9c0f592026043fcb3f11 '   itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock av_inherit_color'  itemprop=\"text\" ><ol>\n<li>0020 Clinical Evaluation Report &#8211; Transit-Pellets ver08 (Internal Document). November 2023.<\/li>\n<li>Abrahamsson, H., Antov, S. &amp; Bosaeus, I. (1988). Gastrointestinal and colonic segmental transit time evaluated by a single abdominal X-ray in healthy subjects and constipated patients. Scand J Gastroenterol. Vol. 23 (suppl 152), 72-80.<\/li>\n<li>Chang, W., et al (2023). American Gastroenterological Association-American College of Gastroenterology Clinical Practice Guideline: Pharmacological Management of Chronic Idiopathic Constipation. The American Journal of Gastroenterology. Vol. 118(6), 936-954.<\/li>\n<li>ED 23-003 The Disorded Bowel \u2013 Transit-Pellets are useful in both ends of the spectrum (Medifactia Internal Document).<\/li>\n<li>Keller, J., Bassotti, G., Clarke, J., et al. (2018). EXPERT CONSENCUS DOCUMENT. Advances in the diagnosis and classification of gastric and intestinal motility disorders [electronic version]. Nat Rev Gastroenterol Hepatol., Vol. 15(5), 291-308.<\/li>\n<li>Cummings, J.H., Jenkins, D.J.A., Wiggins, H.S. (1976). Measurement of the mean transit time of dietary residue through the human gut. Gut. Vol. 17, 210-18.<\/li>\n<\/ol>\n<\/div><\/section><\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-15055","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/medifactia.com\/pl\/wp-json\/wp\/v2\/pages\/15055","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medifactia.com\/pl\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/medifactia.com\/pl\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/medifactia.com\/pl\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/medifactia.com\/pl\/wp-json\/wp\/v2\/comments?post=15055"}],"version-history":[{"count":8,"href":"https:\/\/medifactia.com\/pl\/wp-json\/wp\/v2\/pages\/15055\/revisions"}],"predecessor-version":[{"id":15181,"href":"https:\/\/medifactia.com\/pl\/wp-json\/wp\/v2\/pages\/15055\/revisions\/15181"}],"wp:attachment":[{"href":"https:\/\/medifactia.com\/pl\/wp-json\/wp\/v2\/media?parent=15055"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}