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Clinical Decision Support Tool – Irritable Bowel Syndrome¹

1. https://svenskgastroenterologi.se. The Clinical Decision Algorithm has undergone minor adjustments compared to the original version.

Colonic Transit Time (CTT) in Children and Adolescents: Reference Values

Colonic Transit Time (CTT) values are not normally distributed. Therefore, percentile 95 is often used for upper reference values.

Two studies on totally 76 healthy subjects, 3-18 years, have been performed with the Abrahamsson method (Transit-Pellets method) presenting percentile 95-values (Wagener et al 2004; Vande Velde et al 2013). In both studies the highest CTT value observed was 3.6 days (36 markers, 86.4 hours). In the Wagener study on 22 patient’s, percentile 95 was 3.5 days while in the Vande Velde study on 54 patients the percentile 95 was 3.3 days.

Rintala et al (1997) studied 25 healthy children with the same method. The highest CTT value observed was 3.4 days while percentile 95 was not reported.

For calculation of segmental transit times with the Transit-Pellets method four colonic sub-segments, cecum-ascending colon, transverse colon, descending colon and sigmoid colon-rectum, are usually considered, as done by Wagener et al.

Based on these reports a provisional upper reference value for CTT (percentile 95) of about 3.3 days (approximately 80 hours) in children and adolescents seems reasonable until further studies are conducted on larger groups.

Rintala, R.J., Marttinen, E., Virkola, K., et al (1997). Segmental Colonic Motility in Patients With Anorectal Malformations. Journal of Pediatric Surgery, Vol. 32, No. 3, 453-456.

Vande Velde, S., Notebaert, A., Meersschaut, V., et al (2013). Colon transit time in healthy children and adolescent. Int J Colorectal Dis., Vol. 28, 1721-1724.

Wagener, S., Shankar, R.R., Turnock, G.L., et al., (2004). Colonic Transit Time – What Is Normal? J Pediatr Surg., Vol. 39, 166-169.

Result in Hours

Colonic Transit Time (OATT); Reference Values ^{1, 2, 3}

Normal transit time corresponds to the range from percentile 5 to percentile 95 in the control material. Reference values based on 199 subjects.

Segmental Transit Time; Upper Reference Values ¹

Percentile 95 calculated per segment in healthy subjects.

1. Abrahamsson, H., Antov, S. & Bosaeus, I. (1988). Gastrointestinal and colonic segmental transit time evaluated by a single abdominal X-ray in healthy subjects and constipated patients. Scand J Gastroenterol. Vol. 23 (suppl 152), 72-80.

2. Sadik, R., Abrahamsson, H., Stotzer, P.O. (2003). Gender differences in gut transit shown with a newly developed radiological procedure. Scand. J. Gastroenterol., Vol. 38, 36-42.

3. Törnblom, H., et al. Data on File, Gastrointest Lab, Sahlgrenska University Hospital.

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Placing an order Please order online by filling out the order form below If you have problem you can also order via email; order@medifactia.com Orders by telephone are not possible, sorry
	European Countries We ship direct or via local distributors to all countries within the European Union. We also ship to a list of other non-EU member countries.
	Other countries (America, Africa, Asia, Australia) We ship direct or via local distributors to countries in these regions.
	Payment You can pay with bank transfer (giro transfer, wire transfer). Payment with credit card is not yet possible, sorry.
	Shipping We ship with parcel service DHL. All shipment are insured and can be tracked.
	Delivery time Delivery time depends on the location of your country in the world. Europe: 2-5 days Other countries: 1-2 weeks

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